Showing posts with label health care. Show all posts
Showing posts with label health care. Show all posts

Friday, June 23, 2017

My Thought On Latest Health Care Bill


Scroll down for animated version
of what I call O-Trauma Care!
See Mike Luckovich, Atlanta Journal-Constitution who seems to have coined "O-Trauma-Care" on 4 March 2014, before I independently came up with that term.


Ira Glickstein

Thursday, April 2, 2015

Quality of Life and Quality Adjusted Life Years (QALY)

What is Quality of Life and how is it related to Standard of Living? How should Health-Related Quality of Life play into decisions by individuals, health insurance plans, and government subsidized health care decisions? In particular, how are Quality Adjusted Life Years (QALY) calculated and used to approve or disapprove a given medical procedure by a government or private insurance system?

These are important questions that can have no definitive answers. However, they are well worth discussing in a collegial, rational, and fact-based way.

I presented this Topic to The Villages Philosophy Club in 2012 and updated it for a presentation on 3 April 2015 to the same group. Our meetings draw around 50 people, mostly retirees in their 60's, 70's and 80's.

Participants evaluate which beneficial factors in the "PERSONAL", "PEOPLE", and "THINGS" categories they judge to be the most important factors leading to high Quality of Life. They also use a questionaire called "EQ-5D" to estimate their individual Health-Related Quality of Life levels.

We then discuss the results and the implications for making individual Health Care decisions.The results of our selections and evaluations in 2012 are posted below.

You may view and download the updated, 2015 PowerPoint slides here.

Also see:
END OF LIFE Honest Brokers, not "Death Panels".

"Runaway Trolley" applied to END OF LIFE issues.

WHAT IS QUALITY OF LIFE?

After researching this question on the Internet, and thinking about my own country, community, family, and life, I came to the conclusion that Standard of Living is only one contributor to a high Quality of Life. It is definitely possible to live at a moderate Standard of Living so long as you have other beneficial factors in your life. I came up with a list of some 21 beneficial factors, seven having to do with PERSONAL aspects of our lives, seven with PEOPLE in our lives, and seven with THINGS in our lives, as follows:
PERSONAL
⃝ Higher Education and Knowledge
⃝ Honest, Hard-Working Reputation
⃝ Satisfying, Rewarding Career
⃝ Travel, Hobbies, Recreation and Leisure Time
⃝ Robust Health and Long Life
⃝ Emotional Well-Being
⃝ Strong Religious Faith

PEOPLE
⃝ Loving Parents, Grandparents
⃝ Loving Spouse, Children, Grandchildren
⃝ Loving Siblings and Extended Family
⃝ Great Teachers, Clergy, Bosses, …
⃝ Loyal Friends and Good Neighbors
⃝ Cooperative, Competent Co-Workers
⃝ Competent and Friendly Service People
THINGS
⃝ Freedom and Human Rights
⃝ Stable and Secure Finances
⃝ Comfortable, Safe Home and Community
⃝ High-Tech Electronics and Entertainment
⃝ Fine Food, Fancy Furnishings, High Lifestyle
⃝ Excellent Healthcare
⃝ Golf, Swimming and other Sports Facilities

RESULTS OF THE SURVEY

During my presentation to The Villages Philosophy Club in 2012, nearly 50 people participated in the survey. Each member was asked to vote for his or her top ten items and the scores were tallied and are graphed below to determine the most important in each category and the most important ten in the whole list.

The top "THINGS" items were:
-Freedom and Human Rights, and (tied for second place)
-Stable and Secure Finances, and
-Excellent Healthcare


The top "PERSONAL" items were:
-Robust Health and Long Life, and
-Emptional Well-Being




The top "PEOPLE" items were:
-Loving Spouse, Children, Grands, and
-Loyal Friends, Good Neighbors






The overall top ten items were the ones with their numbers highlighted in pink:

They are:
1-Robust Health and Long Life
2-Freedom and Human Rights
3-Stable and Secure Finances
4-Excellent Healthcare
5-Loving Spouse, CHildren, Grands
6-Comfortable/Safe Home/Community
7-Emotional Well-Being
8-Loyal Friends, Good Neighbors
9-Travel, Hobbies, Recreation, leisure
10-Loving Parents, Grandparents


OTHER MEASURES OF QUALITY OF LIFE

The Human Development Index (see
2014_UN_Human_Development_Report)is a 2014 UN publication that considers life expectancy, literacy, education, standards of living, and other aspects of Quality of Life to come up with a score for each country. Not surprisingly, the highest levels are found in the US, Canada, Western Europe, Japan, Australia, Chile, and Argentina. The lowest in Central Africa and parts of Asia.

The 2013 Where to be born index (formerly Quality of Life Index in 2005) 
(see http://en.wikipedia.org/wiki/Quality-of-life_index for 2013 update) by the respected British magazine The Economist . They consider: 
Healthiness: Life expectancy at birth
Family life: Divorce rate
Community life: High rate of church attendance or trade-union membership
Material well being: GDP per person
Political stability and security: Political stability and security
Climate and geography: Latitude (warmer and colder climates)
Job security: Unemployment rate
Political freedom: Political and civil liberties
Gender equality: Average male and female earnings

Again, the US, Canada, Western Europe, Japan, and Australia get high scores, but, surprisingly, the top country is Switzerland (was Ireland in 2005 version). The US comes in 16th, between Germany and the United Arab Emirates (was 13th, just after Finland and ahead of Canada in 2005 version).

The Happy Planet Index (see http://en.wikipedia.org/wiki/File:Happy_Planet.PNG) is a 2015 update of the 2012 effort that "is not a measure of which are the happiest countries in the world: [but rather a] Measure of the environmental efficiency of supporting well-being in a given country, and of the Subjective life satisfaction, life expectancy at birth, and ecological footprint per capita."

The US comes in at a dismal  #105 in the 2015 rankings, and is in the worst category along with much of Central Africa and Russia. The best three countries in the 2015 ranking is Costa Rica, with a "Happy Planet Index" that is twice that of the US.

WHAT IS HEALTH-RELATED QUALITY OF LIFE?

How should Quality of Life impact health care decisions? Government agencies, including the US Centers for Desease Control and Prevention (CDC) and the UK National Institute for Health and Clinical Excellence (NICE) have considered this question for decades, and their decisions are currrently affecting your health care availability, and will do so more and more in the future.

The US CDC website (see http://www.cdc.gov/hrqol/concept.htm) has links to many Health-Related Quality of Life pages, as does the UK NICE website (see http://www.nice.org.uk/).


Health-Related Quality of Life is measured by several different questionaires, inluding the SF-36 and EQ-5D. The SF-36 (see http://www.anapsid.org/cnd/files/sf36.pdf) consists of 36 multiple-choice questions. The EQ-5D (see
http://www.medicine.ox.ac.uk/bandolier/painres/download/whatis/QALY.pdf) has five multiple-choice quesitions. The result is a personal score that ranges from 1 (for perfect health) to 0 (for death). It is possible to score as low as -0.5 (worse than death).

In 2012 the members of The Villages Philosophy Club took the EQ-5D survey and the average personal score was 0.88, indicating a pretty healthy group. Around 40% of us reported PERFECT HEALTH with a score of 1.0. About 30% reported NEAR-PERFECT HEALTH with a score of 0.88. About 22% (including me) reported the next level down with a score of 0.76. About 4% reported a score of 0.62, and about 2% each reported 0.47 and 0.33.

When a health care decision is to be made between alternative treatments, consideration is given to an estimate of the level of Health-Related Quality of Life that will most likely result from each treatment alternative, as well as an estimate of how long the patient is likely to live if given that treatment. The result of multiplying Health-Related Quality of Life by Years of Life is called the Quality Adjusted Life Years (QALY).

In the UK, if a given treatment alternative costs less than about 30,000 pounds per QALY, and if the doctor and patient want that alternative, it is approved and paid for by the National Health Service. If the desired alternative is more expensive than about 30,000 pounds per QALY, it is denied, and a lower cost (and more cost-effective) alternative is approved. 30,000 pounds is equivalent to about $40,000 - $50,000.

Please feel free to comment. I would love to have an interactive discussion. Click on "Comments" just below my name, type your comment, then choose "Name/URL" and enter your name or nickname (URL not required), and then "Publish". If you are not an "Authorized Author" it may take a day or so for me to moderate your comment and then it will appear.)


Ira Glickstein

Tuesday, November 25, 2014

Squat Toilet ("Squatty Potty" on "Shark Tank")

Want to "POOP BETTER"? The squat position helps me get GOing more easily and finish more completely. A recent episode of Shark Tank (ABC TV) featured a squat toilet product you may purchase at the Squatty Potty website - or you may use my alternative solution inspired by that product (see images below).
I got the black folding step-stool at my local Walmart. It is about 12 inches high. They have smaller ones available in different colors. Images above: 1) Folding step-stool in position. 2) Folded and tucked away, only two inches thick. 3) Unfold the stool. 4) Stool in position with one leg lifted, 5) Both legs up and ready to GO (of course, remember to pull your pants down :^).

The images below, from the official Squatty Potty website, illustrate why a squat toilet works so well.
Your dog and all humans -until relatively recently- naturally squat to fully relax their puborectalis muscles and thereby POOP BETTER. It is amazing to me that the modern toilet allows only partial relaxation of the muscle that prevents you from pooping freely. Despite my positive experiences with the squat position while pooping in the woods, and with squat toilets in Egypt and on other foreign travels, I never thought to try to approximate that position at home. Now that I've adopted the squat position, I cannot GO back :^)

BETTER POOPING TO ALL, AND TO ALL A GOOD LIFE!

Ira Glickstein

Wednesday, February 19, 2014

Alzheimer’s A to Z Presentation to Philosophy Club 2/14/14 (Lee Conrad)


A person’s life is comprised of memories – that’s exactly what Alzheimer’s disease (AD) takes away from you! What makes this so difficult for caregivers: “It’s the living loss of a loved one – still with you; but, slowly drifting away”.

I presented this topic to The Villages Philosophy Club on 14 February 2014 and my Powerpoint slides are available:
https://sites.google.com/site/iraclass/my-forms/Philo%20ALZLHEIMERS%20V4.5.pps?attredirects=0&d=1

The brains of people with AD contain “Plaques” of Amyloid Beta, a protein, and tangles of another protein called tau. By the time a person manifests objectively measurable cognitive impairment, Amyloid-β, (Aß), is strongly positive in the regions of the brain known as the “DEFAULT NETWORK” – which are particularly vulnerable to (Aß) deposition.

Aß can fold into a misshapen form that causes other normal Aß molecules to assume the wrong shape and clump together. Proteins may later break off from the aggregate and seed the beginnings of the same process elsewhere. This biochemical domino effect involves a mechanism called “CORRUPTIVE PROTEIN TEMPLATING”.

As this biochemical domino effect spreads through the brain, this inexorable progression of Aß deposits engulfs most areas of the cerebral cortex (the brains outer layer) progressing to the midbrain finally reaching the lower brainstem and cerebellum in the organ’s deepest reaches.

There are no exact transition points that define when a patient has progressed from the pre-clinical phase to the mild cognitive impairment phase and then to the dementia phase.

Diagnosing dementia involves many factors which include:
o A complete physical
o A complete neurologic examination
o MRI & CT scans of the brain
o Blood & Urine tests
o Thorough discussion of patients medical history & symptoms

All of the above with a qualified neurologist and neuropsychologist

From my personal experience, observing my spouse, I could see signs of cognitive problems that needed to be addressed:
o Problems using the microwave
o Problems using TV remotes
o Problems w/ electronics that have to be programmed
o Difficulty organizing M – F pillbox for AM/PM medications
o Difficulty with driving directions through roundabouts

I obtained from a friend connected with the American Academy of Neurology suggestions for possible Neurologist from various institutions and current publications (April 2013) relevant to Mild Cognitive Impairment (MCI), Alzheimer’s dementia, genetic risk factors for late onset AD, recent genes associated with early onset AD, radioactive biomarkers for PET scans of the brain, and biochemical biomarkers present in cerebrospinal fluid (CSF). I also obtained excellent advice from a former classmate MD (specialty Internal Medicine), with experience diagnosing this disease, and his recommendation: “Seek a well- established neurologist in the field and obtain a blood test for the ApoE gene.

After a 3 - 5 hour initial exam with a neurologist associated with the Brain Institute, and the neurology dept., Shands Hospital, U. FL, Gainesville and psychologists on the staff --- the preliminary diagnosis was possible MCI with orders for a full day of neuropsychological testing, MRI of the brain and follow up in 2 months.

With the preliminary diagnosis of MCI, the review article (April 2013) on MCI was very important. The slides on MCI are self-explanatory regarding it’s clinical characterization and the significant interest in understanding the transition from MCI to AD.

After 8 hours of extensive neuropsychological testing at Shands, the final diagnosis was changed from MCI to early stages of AD, verified by the appearance of hippocampal atrophy, one of the first regions of the brain to suffer damage in AD patients. Blood tests results came back: Genotype *E2/*E4 (*E4 is a strong genetic risk factor for Alzheimer’s).

Recommended treatment: begin memory medication (Aricept) ASAP, returning in 4 months for subsequent evaluation of the effectiveness of the medication.

The blood test results for Genotype APO*E2 / APO*E4, are explained in the AAN Review Article Continuum on New Genes and Insights from old Genes, which explains the significance of APO*E4 as a genetic risk factor for AD, increasing the risk by a factor of 3 to 4 fold.

Subsequent slides explain three other genes strongly associated with “early Onset” Alzheimer’s (prior to age 65 and experiments with APP-Transgenic mice, genetically engineered (with the APP gene) to produce the precursor protein from which the human Aβ fragment is generated and spontaneously develops Aβ brain deposits at a relatively consistent age.

Future Experiments with APP-Transgenic Mice hopefully may yield important clues to solving the problem for early detection and the subsequent prevention of dementia.


Lee Conrad

Tuesday, September 25, 2012

Affordable Food Care Act

Now that the Affordable Healthcare Act (aka "Obamacare") has been declared constitutional by the US Supreme Court, and has gone into effect, it is high time we move into the even more important realm of FOOD CARE.

After all, most of us EAT three times a day (some five times or more) while most of us only require health care a few times a year. If we are deprived of health care, most of us will live on for years, but, if we are deprived of food, even the strongest of us we will survive for only days (or three weeks max).

Having established that FOOD CARE is more critical than Healthcare, let us come up with a solution that will reduce costs and improve quality. Let us take the unfair profits away from the blood-sucking supermarkets by establishing a single-payer food program that will assure the healthiest foods at the lowest possible cost to us and our fellow citizens (and legal and illegal aliens as well, of course).

For example, there are dozens of supermarkets in my Zip Code, all of them profit-based and all making fat profits selling food that is often unhealthy and that has made many of my neighbors sickly and obese. Each of these supermarkets is earning exorbitant profits by jacking up their prices to the highest levels possible. Why should there be more than one food supplier in any given Zip Code? Why should we, the consumers, have to pay the bloated overhead of all these duplicated stores?

THE FOOD CARE SOLUTION

The advent of email, and unfair competition from profit-making UPS and FedEx, has nearly destroyed the United States Post Office. Most of their buildings are underutilized and they require large subsidies to continue operation and pay their employees.

The FOOD CARE solution is OBVIOUS. Turn FOOD distribution over to the real delivery experts at the US Post Office and FOOD acquisition over to the real nutrition experts at the US Agriculture Department. Make fresh, healthy food available for free, delivered seven days a week directly to every home in America. Letter Carriers will once again have full mailbags. Since they already deliver mail six days a week, adding a seventh day will not raise costs by more than 15%.  By eliminating profits, costs will go down, and by eliminating unhealthy foods, there will be large savings in the public health care system.

Everyone will be required to purchase Food Care Insurance and those who refuse to do so will be charged a $500 tax per year (but only if they can afford it). In that way:

- Everyone in our great country will be assured three square meals a day!

- Fresh food will be delivered daily, eliminating the cost of weekly trips to the supermarket and the expense of household refrigerators and freezers as well as the Global Warming imposed by the energy demands imposed by unnecessary travel and household appliances.

- And disabilities due to unhealthy, fattening and sugar-filled foods will be a thing of the past!

- And health-care costs will go down as life-expectancy goes way up!

- And, the US Post Office, a cherished memory of government services at their best, will survive and prosper!

What could possibly be wrong with this plan?

Ira Glickstein

UPDATE 27 Sep 2012 
 
Howard Pattee posted a comment on 26 Sep regarding US Health Care costs, and why they are so much higher than other countries. I did some research on why US health care costs have risen so fast and concluded that about half the increase is due to medical technology advances that were not available in the past and that are both increasing lifetimes and are very expensive.

However, it appears (see chart below) that the other half of the rapid increase in costs is driven by government programs where a third-party (US Taxpayer) is paying and the consumer gets the care for "free" so they have no reason to shop around or limit their consumption and, as a result, suppliers have no incentive to contain costs. This almost completely eliminates normal market forces that balance supply and demand according to cost and affordability.

My (sarcastic) example of "free" food supplied by the government was meant to show how ridiculous it would be to remove market forces that improve quality and convenience and keep costs affordable.  Milton Freedman said that if the government was put in charge of the Sahara Desert, within six years there would be a shortage of sand! And the cost of sand would skyrocket as the quality declined.

In other countries, notably the UK, medical costs are contained by rationing care based on a limit of about $40,000 per additional Quality-Adjusted Life Year (QALY). If a given procedure would increase the lifetime and quality of life of the recipient, but exceeds the cost limit per QALY, an alternate, less expensive procedure, such as palliative care, will be provided.

For the record, I wrote about the QALY concept way back in 2009 see http://tvpclub.blogspot.com/2009/09/end-of-life-honest-brokers-not-death.html and I support it for public medical expenditures in the US.

(More recently, see http://tvpclub.blogspot.com/2011/02/runaway-trolley-applied-to-end-of-life.html, and http://tvpclub.blogspot.com/2012/08/quality-of-life-and-health-related.html for my views. Unless we thoughtfully address End of Life and rationing of health care for people with chronic and terminal conditions, we will never be able to control overspending on health care. A false sense of "compassion" and "fairness" and "caring" will continue to bankrupt the USA.)

Friday, August 3, 2012

Quality of Life and Health-Related Quality of Life

What is Quality of Life and how is it related to Standard of Living? How should Health-Related Quality of Life play into decisions by individuals, health insurance plans, and government subsidized health care decisions?

These are important questions that can have no definitive answers. However, they are well worth discussing in a collegial, rational, and fact-based way.

I presented this Topic to The Villages Philosophy Club today and had the nearly 50 people who attended, mostly retirees in their 60's, 70's and 80's, select what they judged to be the most important factors leading to high Quality of Life. They also used a questionaire called "EQ-5D" to estimate their individual Health-Related Quality of Life levels. We then discussed the results and the implications for making individual Health Care decisions.The results of our selections and evaluations are posted below.

You may view and download the PowerPoint slides here: https://sites.google.com/site/iraclass/my-forms/QualityOfLife3Aug2012.pptx?attredirects=0&d=1


WHAT IS QUALITY OF LIFE?

After researching this question on the Internet, and thinking about my own country, community, family, and life, I came to the conclusion that Standard of Living is only one contributor to a high Quality of Life. It is definitely possible to live at a moderate Standard of Living so long as you have other beneficial factors in your life. I came up with a list of some 21 beneficial factors, seven having to do with Personal aspects of our lives, seven with People in our lives, and seven with Things in our lives, as follows:
PERSONAL
⃝ Higher Education and Knowledge
⃝ Honest, Hard-Working Reputation
⃝ Satisfying, Rewarding Career
⃝ Travel, Hobbies, Recreation and Leisure Time
⃝ Robust Health and Long Life
⃝ Emotional Well-Being
⃝ Strong Religious Faith

PEOPLE
⃝ Loving Parents, Grandparents
⃝ Loving Spouse, Children, Grandchildren
⃝ Loving Siblings and Extended Family
Great Teachers, Clergy, Bosses, …
Loyal Friends and Good Neighbors
Cooperative, Competent Co-Workers
⃝ Competent and Friendly Service People

THINGS
⃝ Freedom and Human Rights
⃝ Stable and Secure Finances
⃝ Comfortable, Safe Home and Community
⃝ High-Tech Electronics and Entertainment
⃝ Fine Food, Fancy Furnishings, High Lifestyle
⃝ Excellent Healthcare
⃝ Golf, Swimming and other Sports Facilities

RESULTS OF THE SURVEY

During my presentation to The Villages Philosophy Club today, nearly 50 people participated in the survey. Each member was asked to vote for his or her top ten items and the scores are tallied and graphed below to determine the most important two in each category and the most important ten in the whole list.
The top "THINGS" items were:
-Freedom and Human Rights, and (tied for second place)
-Stable and Secure Finances, and
-Excellent Healthcare


The top "PERSONAL" items were:
-Robust Health and Long Life, and
-Emptional Well-Being




The top "PEOPLE" items were:
-Loving Spouse, Children, Grands, and
-Loyal Friends, Good Neighbors


The overall top ten items were the ones with their numbers highlighted in pink:

They are:
1-Robust Health and Long Life
2-Freedom and Human Rights
3-Stable and Secure Finances
4-Excellent Healthcare
5-Loving Spouse, CHildren, Grands
6-Comfortable/Safe Home/Community
7-Emotional Well-Being
8-Loyal Friends, Good Neighbors
9-Travel, Hobbies, Recreation, leisure
10-Loving Parents, Grandparents


OTHER MEASURES OF QUALITY OF LIFE

The Human Development Index (see
http://en.wikipedia.org/wiki/File:2011_UN_Human_Development_Report_Quartiles.svg) is a 2011 UN publication that considers life expectance, literacy, education, standards of living, and other aspects of Quality of Life to come up with a score for each country. Not surprisingly, the highest levels are found in the US, Canada, Western Europe, Japan, Australia, Chile, and Argentina. The lowest in Central Africa and parts of Asia.

The Quality of Life Index (see http://en.wikipedia.org/wiki/Quality-of-life_index) was put out in 2005 by the respected British magazine The Economist and they consider:
Healthiness: Life expectancy at birth
Family life: Divorce rate


Community life: High rate of church attendance or trade-union membership
Material well being: GDP per person
Political stability and security: Political stability and security
Climate and geography: Latitude (warmer and colder climates)
Job security: Unemployment rate
Political freedom: Political and civil liberties
Gender equality: Average male and female earnings

Again, the US, Canada, Western Europe, Japan, and Australia get high scores, but, surprisingly, the top country is Ireland. The US comes in 13th, just after Finland and ahead of Canada.

The Happy Planet Index (see http://en.wikipedia.org/wiki/File:Happy_Planet.PNG) is a 2006-2012 effort that "is not a measure of which are the happiest countries in the world: [but rather a]
Measure of the environmental efficiency of supporting well-being in a given country, and of the Subjective life satisfaction, life expectancy at birth, and ecological footprint per capita. 

The US comes in at a dismal  #114 in the 2009 rankings, and is in the worst category along with much of Central Africa and Russia. The best three countries in the 2012 ranking are Costa RIca, Vietnam, and Columbia which each have a "Happy Planet Index" that is twice that of the US.

WHAT IS HEALTH-RELATED QUALITY OF LIFE?

How should Quality of Life impact health care decisions? Government agencies, including the US Centers for Desease Control and Prevention (CDC) and the UK National Institute for Health and Clinical Excellence (NICE) have considered this question for decades, and their decisions are currrently affecting your health care availability, and will do so more and more in the future.

The US CDC website (see http://www.cdc.gov/hrqol/concept.htm) has links to many Health-Related Quality of Life pages, as does the UK NICE website (see http://www.nice.org.uk/).


Health-Related Quality of Life is measured by several different questionaires, inluding the SF-36 and EQ-5D. The SF-36 (see http://www.anapsid.org/cnd/files/sf36.pdf) consists of 36 multiple-choice questions. The EQ-5D (see
http://www.medicine.ox.ac.uk/bandolier/painres/download/whatis/QALY.pdf) has five multiple-choice quesitions. The result is a personal score that ranges from 1 (for perfect health) to 0 (for death). It is possible to score as low as -0.5 (worse than death).

The members of The Villages Philosophy Club took the EQ-5D survey and the average personal score was 0.88, indicating a pretty healthy group. Around 40% of us reported PERFECT HEALTH with a score of 1.0. About 30% reported NEAR-PERFECT HEALTH with a score of 0.88. About 22% (including me) reported the next level down with a score of 0.76. About 4% reported a score of 0.62, and about 2% each reported 0.47 and 0.33.

When a health care decision is to be made between alternative treatments, consideration is given to an estimate of the level of Health-Related Quality of Life that will most likely result from each treatment alternative, as well as an estimate of how long the patient is likely to live if given that treatment. The result of multiplying Health-Related Quality of Life by Years of Life is called the Quality Adjusted Life Years (QALY).

In the UK, if a given treatment alternative costs less than about 30,000 pounds per QALY, and if the doctor and patient want that alternative, it is approved and paid for by the National Health Service. If the desired alternative is more expensive than about 30,000 pounds per QALY, it is denied, and a lower cost (and more cost-effective) alternative is approved. 30,000 pounds is equivalent to about $47,000.


Ira Glickstein